Overproduction of IL-7, IL-10 and TGF-β1 in Multiple Myeloma

Regular paper TGF-β1, IL-10 and IL-4 in colostrum of allergic and nonallergic mothers

Objective: To determine transforming growth factor (TGF) β1, interleukin (IL) 4, and IL-10 concentrations in human milk and to assess the relationship between allergic disorders in mothers and the content of the interleukins in their milk. Material and methods: Thirty allergic and 46 healthy mothers were included in the study. Colostrum was collected 2–3 days after delivery. Cytokine concentrat...

Effects of aerobic training in water on IL-6 and IL-10 in patients with Multiple Sclerosis

Background: Multiple Sclerosis is the most prevalent disease of the central nerve system. This disease affects different aspects of patient’s life. Multiple Sclerosis has negative effects on physical and mental health. Cytokines play an important role in the pathogenesis of Multiple Sclerosis and are major targets of therapeutic interventions. Aim: To investigate the effects of aquatic aerobic ...

Gene Polymorphisms of Immunoregulatory Cytokines IL-10 and TGF-β1 in Systemic Lupus Erythematosus

Association between TNF-α, TGF-β1, IL-10, IL-6 and IFN-γ gene polymorphisms and generalized aggressive periodontitis

Objective: The aim of this study was to investigate links among cytokine genetic variants and generalized aggressive periodontitis (GAgP). Methods: Thirty-five patients with generalized aggressive periodontitis and 85 healthy controls without periodontitis were included in the study. Probing depth (PD), clinical attachment loss (CAL), plaque index (PI), and gingival index (GI) were recorded as ...

Natural Killer Cell Cytotoxicity and Immunosuppressive Cytokines (IL-10, TGF-β1) in Patients with Gastric Cancer

Cytotoxic activity of NK cells was estimated as related to IL-10 and TGF-beta1 serum levels and Helicobacter pylori infection in gastric cancer patients. Moreover, we sought to determine whether human gastric adenocarcinoma cells in vitro release IL-10, TGF-beta1 or factor(s) affecting NK cytotoxicity. The studies were conducted on 42 patients with gastric cancer (14 with I-II stage-group 1; 28...